Bioluminescent Surface Biosensors For Real-Time Pathogen Detection In Hospitals: A Sustainable Approach To Infection Control

Abstract

Hospital-acquired infections (HAIs) have turned out to be one of the important factors in healthcare operating costs and patient morbidity around the world. The study introduces a novel, environmentally friendly bioluminescent biosensor system that ensures the real-time detection of surface contamination visibly caused by hospital pathogens. The paper discusses the process of creation of a visual warning system that reacts within 30 minutes after coming into contact with pathogens like Escherichia coli and Staphylococcus aureus by designing light-emitting bacteria that are sensitive to pathogens and entrench them in hydrogel films that are attuned with hospital surfaces. The process shows potential for enhancing infection control and creating sustainable healthcare environments by providing a low-energy, non-invasive substitute to substantial surface monitoring and chemical disinfection.