A Study On Reserve Antibiotic Use And Clinical Outcomes In Geriatric Patients

Abstract

In clinical settings, using high-end or restricted antibiotics in elderly patients is a significant problem, especially when treating infections in senior individuals who have other comorbidities. The prescribing practices, safety, effectiveness, and clinical results related to the use of limited antibiotics in elderly individuals in a tertiary care hospital are assessed in this research.

The aim of the study was to access the clinical results, safety profile, and prescribing patterns of limited antibiotics in elderly individuals. Analyzing the effects of comorbidities on prescribing patterns, finding adverse events linked to antibiotics, and investigating the demographic factors impacting antibiotic use were among the particular goals.

163 elderly adults were enrolled in this six-month prospective observational study at a tertiary care facility. Comorbidities, clinical outcomes, antibiotic prescriptions, and patient demographics were among the information gathered. IBM SPSS was used for statistical analysis, and chi-square tests were used to evaluate the correlations between the variables.

The study found that the majority of people with comorbid conditions including diabetes and hypertension have were given restricted antibiotic prescriptions. The most often given antibiotic was meropenem. In 78.5% of cases, the therapeutic use of antibiotics was supported by microbiological data. According to clinical results, 31.9% of patients recovered, while 64.4% of patients remained stable. Adverse instances, which includes as bleeding and gastrointestinal problems, occurred in 42.7% of patients. A considerable percentage of elderly patients who receive limited antibiotics experience stability or recovery, indicating favorable clinical outcomes. However, the frequency of adverse events emphasizes the need for customized treatment regimens and careful monitoring. The findings highlight the importance of improving diagnostic capabilities and implementing comprehensive antibiotic stewardship programs to optimize utilization of antibiotics in the elderly.